10 Best Numbing Creams in 2019

Uber Number 5% Lidocaine Pain Relief Cream

The Uber Number 5% cream is an incredibly strong ointment that delivers great results and fast-acting pain relief. The results last for up to five hours or more, depending on the severity of the pain and it has a non-greasy formula that sinks in quickly.

Lidocaine Plus Maximum Strength

Lidocaine Plus is a versatile and potent treatment at a budget-friendly price, containing 4% lidocaine and aloe vera to sooth the skin and provide lasting pain relief from a number of injuries or conditions, from cysts and pimples to joint pain.

Penetrex Pain Relief Therapy

A versatile and convenient cream that offers quick and long-lasting relief from pain, Penetrex is great as a remedy for conditions such as fibromyalgia, injuries and everyday pain from arthritis. It includes powerful ingredients along with soothing oils and vitamin E.

Numbing cream buyers guide

Numbing creams are popular with people who suffer from extreme pain, such as those who partake in extreme sports, or with people who have ongoing pain-related issues like arthritis or chronic back pain. They’re also commonly purchased by people who get tattoos or laser treatments, as it helps to alleviate some of the pain and discomfort associated with them. Numbing creams usually have a topical application that relieves and blocks pain, and they come in a variety of concentrations depending on what they’re being used for. They usually contain lidocaine or tetracaine as the active ingredient, although some contain benzocaine or prilocaine, although these are less common.

Numbing creams are a useful medication to have on hand in your bathroom cabinet for times when you experience muscle soreness, joint pain or wounds. When choosing a numbing cream, it’s important to note what you will be using it for so you can purchase a cream that’s best suited to those needs. For example, some numbing creams are designed specifically for tattoo enthusiasts who want something to help alleviate pain in sensitive areas of the body while others want something for joint or muscle soreness, or even open wounds and burns, to minimize the pain.

It’s also worth noting that some creams have stronger concentrations of active ingredients which may limit where they can be used, such as on the face, so understanding where it will be applied most often will help you decide on the best product. These are ten of the best numbing creams on the market for a host of different uses and budgets.

Penetrex Pain Relief medication can be used as part of your daily routine as an effective form of pain relief for numerous types of discomfort. This is a fast-acting formula that’s packed with powerful ingredients such as arnica, cetyl myristoleate and vitamin B6 that can be used for conditions such as carpal tunnel syndrome. Penetrex makes targeting pain really easy and is convenient, so you can get immediate results virtually straight away. It has a long-lasting effect and is restorative, with natural ingredients such as sunflower seed oil and vitamin E to make it soothing to the skin. Great for pain in the knees, tendonitis, back pain and fibromyalgia, there are many uses for Penetrex, making it a versatile item to have in your bathroom cupboard.


Key features:

  • Long-lasting formula that alleviates discomfort quickly
  • Can be used in conjunction with complementary therapies such as heating pads, ice packs or sciatica cushions
  • Uses clinically-proven ingredients such as arnica, choline and vitamin B6

The perfect option if you’re on the lookout for a tattoo numbing cream, Hustle Butter Deluxe has softening ingredients that help your skin to heal and reduces pain. It has a pleasant smell and the formulation helps to moisturize the skin to ensure it heals efficiently, reducing irritations. Each application of Hustle Butter lasts several hours as well, so it’s long-lasting and you only need a small amount. It prevents the skin from swelling or bleeding, and reduced inflammation thanks to the green tea extract is contains. It’s efficient at reducing pain almost straight away, with a lasting effect that will keep pain at bay for several hours before you need to reapply so it’s great for bust people who are on the go. For other great health items see our best acne face washes picks.


Key features:

  • Great for tattoos at every stage of the process, preparing the skin and helping to keep it moisturized afterwards
  • Reduces redness and swelling, as well as promoting healing
  • Contains soothing ingredients such as Vitamin E, Green Tea, Rice Bran oils and coconut

This great budget pick is safe and easy to use but still highly effective. It’s a useful cream to have on hand for numerous conditions or painful injuries, from tattoos to wounds and even burns and pimples. Lidocaine Plus is a potent formula that will numb nerve pain and soothes discomfort quickly, with effects that can last up to several hours. It’s designed for external use only but can be used on practically any area of the body where you’re experiencing pain. And because of the numbing effect, it can also be used prior to painful treatments such as tattoos, piercings or laser treatments to prepare the skin beforehand by applying up to an hour before you begin the treatment. From cysts to knee pain and neuropathy, this is a versatile treatment.


Key features:

  • A maximum strength cream that is highly effective at curing pain for a number of different conditions
  • Contains aloe vera for a soothing but powerful formula
  • Made with 4% lidocaine hydrochloride so can be used in small doses with a strong effect

A great product for massaging onto larger muscle areas such as the back or joints where you’re experiencing pain, the Biofreeze Professional Pain Relieving Gel uses menthol and a herbal blend to alleviate pain. It’s free from addictive substances so it’s great for people looking for a more natural and skin-friendly approach to removing discomfort from joints and muscles. The gel has a cooling sensation that delivers long-lasting treatment and is a topical analgesic that professionals such as chiropractors rely on to help with joint pain on their patients. It dries quickly and reduces inflammation quickly for a fast treatment. From bruises and sprains to arthritis, backaches and joint pain, Biofreeze provides a convenient and safe solution to pain management.


Key features:

  • Professional formulation that includes a blend of herbs and menthol as the active ingredient
  • Useful treatment for backaches, arthritis and sore muscles
  • Free from parabens, salicylates, NSAIDs and addictive substances

The LMX 4 Topical Anesthetic Cream is designed to provide effective numbing for laser treatments and injections, with 4% lidocaine delivering the numbing sensation. It reduces up to 75% of the pain experienced from laser treatments, skin surgeries, tattoo removal and even sunburn from outdoor tanning lotions, making it a versatile product. It can also be used as a treatment for minor skin irritations and can be applied topically up to four times a day, removing pain from minor burns or cuts as well. If you’re experiencing irritation or itching from stings from poison ivy, poison oak or from insect bites, this is a useful product to have around that will help take away the discomfort associated with these issues to allow your skin to fully heal without you scratching or itching it and inflaming it further.


Key features:

  • A perfect treatment for tattoo removals, injections or laser treatments
  • Contains 4% lidocaine and can be used up to 4 times a day
  • Treats skin irritations and swelling

Designed as a pre-treatment, the Uber Number 5% lidocaine cream is a potent solution that can be used for tattooing, laser treatments and minor skin surgeries and to alleviating swelling. It has a moisturizing effect too that helps to prevent itching and flaking on the skin, due to the vitamin E in the formula. This is a powerful topical number that delivers super-strong pain relief as it contains a higher percentage of lidocaine compared to other creams on the market. This is the highest dose the FDA will allow for a non-prescription anesthetic. The cream begins working immediately upon absorption into the skin and within 20 minutes it will have achieved the full numbing effect, lasting for over an hour. There’s no oily residue to worry about and it absorbs quickly and effectively into the skin, without causing any stickiness or leaving marks on clothing. For other great health picks see our top fungal nail treatments.


Key features:

  • Lasts up to five hours
  • Is a non-oily formula that can be removed easily as well
  • Great for tattoos in sensitive areas to help make the pain more bearable

The Numb Master Topical Anesthetic cream contains liposomal lidocaine that is approved by the FDA for treating pain in a variety of spots around the body, from joints to simply reducing inflammation in the skin. It works by numbing the upper epidermal layers of the skin making it a great choice for dermalogical procedures. It works within 25 minutes of applying the cream and has a non-oily texture, so it can be used on the face too but can be removed easily using just an everyday cleanser and water. It has a high level of lidocaine for a strong and powerful numbing effect for an over-the-counter treatment.


Key features:

  • A pre-treatment gel that contains 5% lidocaine
  • A non-oily and non-sticky formula that absorbs quickly
  • Numbing effects occurs within 20-25 minutes

Small but mighty, the Lidocaine Blue Gel Topical Anesthetic Cream Gel has a powerful 5% lidocaine concentration combined with 2% tetracine that works incredibly fast. It delivers instant pain relief compared to other creams which can take 20 to 30 minutes to reach their maximum numbing effect. The two active ingredients work together with a vascular constrictor which lowers the risk of swelling or bruising and is ideal for areas such as inner arms or lips where bleeding and bruising are a particular issue. If you don’t tolerate pain well and are undergoing a treatment that is pain-sensitive, such as microblading or tattooing, this is a great product to have to hand. It is safe and works well for use on broken skin too, desensitizing the area without causing any additional harm or irritation. For other health items see our top picks for electric toothbrushes.


Key features:

  • Contains 5% of lidocaine for a powerful numbing effect
  • Tailor-made for people with a low pain threshold to help them tolerate pain more easily
  • Reduces swelling and inflammation during pain-sensitive procedures

Medinumb Lidocaine Numbing Cream is a maximum strength treatment that soothes the skin and reduces swelling. The cream contains a 4% concentration of lidocaine along with three botanical ingredients – tea tree oil, jojoba and aloe vera – for a powerful topical ointment that really works. It has an antibacterial effect that helps to repair the skin and minimize inflammation, while also desensitizing the skin’s receptors for a numbing effect that lasts up to two hours. It’s the ideal treatment for pain-sensitive procedures and surgeries, from tattoos and laser treatments to injections and shots.


Key features:

  • Uses a mix of botanical ingredients with 4% lidocaine for an effective numbing treatment
  • Lasts for up to two hours
  • Clothes-friendly and non-oily formula

A strong cream that targets pain receptors without aggravating nerves, the Aspercreme Pain Relieving Cream provides quick and effective temporary pain relief for issues such as arthritis, back or joint pain, muscle strains and bruises. It’s an odor-free formula that works quickly to reduce pain and inflammation, so it’s a great product to carry with you when you know you have a busy day ahead and will need to reapply throughout the day to keep discomfort at bay. This is a highly effective product that delivers great results, even for people who suffer with regular stubborn pain issues. For other health products see our review on indoor tanning lotions.


Key features:

  • Includes 4% lidocaine to combat strong pain
  • Great for people suffering with arthritis, chronic back pain and sprains
  • Easy to apply and doesn’t leave stains or marks on clothes, so can be reapplied throughout the day